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16 p, 3.2 MB |
Cloxacillin plus fosfomycin versus cloxacillin alone for methicillin-susceptible Staphylococcus aureus bacteremia : a randomized trial
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Grillo, Sara (Hospital Universitari de Bellvitge) ;
Pujol, Miquel (Hospital Universitari de Bellvitge) ;
Miró, José M (Hospital Clínic i Provincial de Barcelona) ;
López-Contreras, Joaquín (Institut d'Investigació Biomèdica Sant Pau) ;
Euba, Gorane (Hospital Universitario Cruces) ;
Gasch Blasi, Oriol (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Boix-Palop, Lucía (Hospital Universitari Mútua Terrassa) ;
Garcia-País, Maria José (Instituto de Investigación Sanitaria de Santiago) ;
Pérez-Rodríguez, Maria Teresa (Complexo Hospitalario Universitario de Vigo) ;
Gómez-Zorrilla, Silvia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Oriol, Isabel (Hospital de Sant Joan Despi Moises Broggi) ;
López-Cortés, Luis Eduardo (Universidad de Sevilla) ;
Pedro-Botet, Maria Luisa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
San-Juan, Rafael (Hospital Universitario 12 de Octubre) ;
Aguado, José María (Universidad Complutense de Madrid) ;
Gioia, Francesca (Instituto Ramon y Cajal de Investigacion Sanitaria) ;
Iftimie, Simona (Hospital Universitari de Sant Joan) ;
Morata, Laura (Hospital Clínic i Provincial de Barcelona) ;
Jover-Sáenz, Alfredo (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
García-Pardo, Graciano (Hospital Universitari Joan XXIII de Tarragona) ;
Loeches, Belén (Hospital Universitario La Paz (Madrid)) ;
Izquierdo-Cárdenas, Álvaro (Institut d'Investigació Biomèdica Sant Pau) ;
Goikoetxea, Ane Josune (Instituto de Investigación Sanitaria Biocruces Bizkaia) ;
Gomila, Aina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Dietl, Beatriz (Hospital Universitari Mútua Terrassa) ;
Berbel, Dàmaris (Hospital Universitari de Bellvitge) ;
Videla, Sebastián (Hospital Universitari de Bellvitge) ;
Hereu, Pilar (Hospital Universitari de Bellvitge) ;
Padullés, Ariadna (Hospital Universitari de Bellvitge) ;
Pallarès, Natalia (Institut d'Investigació Biomèdica de Bellvitge) ;
Tebé, Cristian (Institut d'Investigació Biomèdica de Bellvitge) ;
Cuervo, Guillermo (Hospital Clínic i Provincial de Barcelona) ;
Carratalà, Jordi (Universitat de Barcelona) ;
Universitat Autònoma de Barcelona
Treatment failure occurs in about 25% of patients with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia. We assessed whether cloxacillin plus fosfomycin achieves better treatment success than cloxacillin alone in hospitalized adults with MSSA bacteremia. [...]
2023 -  10.1038/s41591-023-02569-0
Nature Medicine, Vol. 29 (october 2023) , p. 2518-2525
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32 p, 9.6 MB |
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
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Duperron, Marie-Gabrielle (Bordeaux University Hospital(França)) ;
Knol, Maria J. (Erasmus MC University Medical Center) ;
Le Grand, Quentin (Bordeaux Population Health Research Center) ;
Evans, Tavia E. (Erasmus MC University Medical Center) ;
Mishra, Aniket (University of Bordeaux) ;
Tsuchida, Ami (University of Bordeaux) ;
Roshchupkin, Gennady V (Erasmus MC University Medical Center) ;
Konuma, Takahiro (Osaka University Graduate School of Medicine) ;
Trégouët, David-Alexandre (University of Bordeaux) ;
Romero, Jose Rafael (The Framingham Heart Study) ;
Frenzel, Stefan (University Medicine Greifswald) ;
Luciano, Michelle (University of Edinburgh) ;
Hofer, Edith (Medical University of Graz) ;
Bourgey, Mathieu (McGill University) ;
Dueker, Nicole D. (University of Miami) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hilal, Saima (National University of Singapore and National University Health System) ;
Tankard, Rick M. (Curtin University) ;
Dubost, Florian (Erasmus MC University Medical Center) ;
Shin, Jean (University of Toronto) ;
Saba, Yasaman (Medical University of Graz) ;
Armstrong, Nicola (Curtin University) ;
Bordes, Constance (Bordeaux Population Health Research Center) ;
Bastin, Mark E. (University of Edinburgh) ;
Beiser, Alexa (Boston University School of Public Health) ;
Brodaty, Henry (Dementia Collaborative Research Centre Assessment and Better Care) ;
Bülow, Robin (University Medicine Greifswald) ;
Carrera, Caty (Institut d'Investigació Biomèdica Sant Pau) ;
Chen, Christopher (National University of Singapore) ;
Cheng, Ching-Yu (Duke-NUS Medical School) ;
Deary, Ian J. (University of Edinburgh) ;
Gampawar, Piyush G. (Medical University of Graz) ;
Himali, Jayandra J. (UT Health San Antonio) ;
Jiang, Jiyang (University of New South Wales) ;
Kawaguchi, Takahisa (Kyoto University Graduate School of Medicine) ;
Li, Shuo (Boston University School of Public Health) ;
Macalli, Melissa (University of Bordeaux) ;
Marquis, Pascale (McGill University) ;
Morris, Zoe (Royal Infirmary of Edinburgh) ;
Muñoz Maniega, Susana (UK Dementia Research Institute Centre at the University of Edinburgh) ;
Miyamoto, Susumu (Kyoto University Hospital) ;
Okawa, Masakazu (Kyoto University Graduate School of Medicine) ;
Paradise, Matthew (University of New South Wales) ;
Parva, Pedram (Harvard Medical School) ;
Rundek, Tatjana (University of Miami) ;
Sargurupremraj, Muralidharan (University of Bordeaux) ;
Schilling, Sabrina (University of Bordeaux) ;
Setoh, Kazuya (Shizuoka Graduate University of Public Health) ;
Soukarieh, Omar (University of Bordeaux) ;
Tabara, Yasuharu (Shizuoka Graduate University of Public Health) ;
Teumer, Alexander (University Medicine Greifswald) ;
Thalamuthu, Anbupalam (University of New South Wales) ;
Trollor, Julian (UNSW) ;
Valdés Hernández, Maria C. (University of Edinburgh) ;
Vernooij, Meike W. (Erasmus MC University Medical Center) ;
Völker, Uwe (University Medicine Greifswald) ;
Wittfeld, Katharina (German Center for Neurodegenerative Diseases) ;
Wong, Tien Yin (Tsinghua University) ;
Wright, Margaret J. (University of Queensland) ;
Zhang, Junyi (Peking Union Medical College Hospital) ;
Zhao, Wanting (Duke-NUS Medical School) ;
Zhu, Yi-Cheng (Peking Union Medical College Hospital) ;
Schmidt, Helena (Medical University of Graz) ;
Sachdev, Perminder S. (Prince of Wales Hospital (Australia)) ;
Wen, Wei (University of New South Wales) ;
Yoshida, Kazumichi (Kyoto University Graduate School of Medicine) ;
Joutel, Anne (Université Paris Cité) ;
Satizabal, Claudia L. (UT Health San Antonio) ;
Sacco, Ralph L. (University of Miami) ;
Bourque, Guillaume (McGill University) ;
Lathrop, Mark (Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University) ;
Paus, Tomas (University of Toronto) ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Yang, Qiong (Boston University School of Public Health) ;
Mazoyer, Bernard (Bordeaux University Hospital (França)) ;
Boutinaud, Philippe (Fealinx) ;
Okada, Yukinori (University of Tokyo) ;
Grabe, Hans J. (German Center for Neurodegenerative Diseases) ;
Mather, Karen A (Neuroscience Research Australia) ;
Schmidt, Reinhold (Medical University of Graz) ;
Joliot, Marc (University of Bordeaux) ;
Ikram, M. Arfan (Erasmus MC University Medical Center) ;
Matsuda, Fumihiko (Kyoto University Graduate School of Medicine) ;
Tzourio, Christophe (Bordeaux University Hospital(França)) ;
Wardlaw, Joanna (University of Edinburgh) ;
Seshadri, Sudha (UT Health San Antonio) ;
Adams, Hieab (Universidad Adolfo Ibáñez) ;
Debette, Stéphanie (Bordeaux University Hospital(França)) ;
Universitat Autònoma de Barcelona
Perivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia. Genome-wide association studies in up to 40,095 participants (18 population-based cohorts, 66. [...]
2023 - 10.1038/s41591-023-02268-w
Nature Medicine, Vol. 29 (april 2023) , p. 950-962
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33 p, 1.9 MB |
The Consensus Molecular Subtypes of Colorectal Cancer
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Guinney, Justin (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ;
Dienstmann, Rodrigo (Vall d'Hebron Institut d'Oncologia) ;
Wang, Xin (City University of Hong Kong. Department of Biomedical Sciences (China)) ;
de Reyniès, Aurélien (Ligue Nationale Contre le Cancer (France)) ;
Schlicker, Andreas (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ;
Soneson, Charlotte (SIB Swiss Institute of Bioinformatics (Switzerland)) ;
Marisa, Laetitia (Ligue Nationale Contre le Cancer (France)) ;
Roepman, Paul (Agendia NV (Netherlands)) ;
Nyamundanda, Gift (The Institute of Cancer Research (UK)) ;
Angelino, Paolo (SIB Swiss Institute of Bioinformatics (Switzerland)) ;
Bot, Brian M. (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ;
Morris, Jeffrey S. (The University of Texas M.D. Anderson Cancer Center (USA)) ;
Simon, Iris M. (Agendia NV (Netherlands)) ;
Gerster, Sarah (SIB Swiss Institute of Bioinformatics (Switzerland)) ;
Fessler, Evelyn (University of Amsterdam (Netherlands)) ;
de Sousa e Melo, Felipe (University of Amsterdam (Netherlands)) ;
Missiaglia, Edoardo (SIB Swiss Institute of Bioinformatics (Switzerland)) ;
Ramay, Hena (SIB Swiss Institute of Bioinformatics (Switzerland)) ;
Barras, David (SIB Swiss Institute of Bioinformatics (Switzerland)) ;
Homicsko, Krisztian (Ecole Polytechnique Federale de Lausanne (Switzerland)) ;
Maru, Dipen (The University of Texas M.D. Anderson Cancer Center, Houston (USA)) ;
Manyam, Ganiraju C. (The University of Texas M.D. Anderson Cancer Center, Houston (USA)) ;
Broom, Bradley (The University of Texas M.D. Anderson Cancer Center, Houston (USA)) ;
Boige, Valerie (Gustave Roussy, Villejuif (France)) ;
Perez-Villamil, Beatriz (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Laderas, Ted (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ;
Salazar, Ramon (Institut d'Investigació Biomèdica de Bellvitge) ;
Gray, Joe W. (Oregon Health Sciences University (USA)) ;
Hanahan, Douglas (Ecole Polytechnique Federale de Lausanne (Switzerland)) ;
Tabernero, Josep (Vall d'Hebron Institut d'Oncologia) ;
Bernards, Rene (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ;
Friend, Stephen H. (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ;
Laurent-Puig, Pierre (Universite Paris Descartes (France)) ;
Medema, Jan Paul (LEXOR, Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam (Netherlands)) ;
Sadanandam, Anguraj (The Institute of Cancer Research (UK)) ;
Wessels, Lodewyk (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ;
Delorenzi, Mauro (University of Lausanne (Switzerland)) ;
Kopetz, Scott (The University of Texas M.D. Anderson Cancer Center (USA)) ;
Vermeulen, Louis (LEXOR, Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam (Netherlands)) ;
Tejpar, Sabine (Universitair ziekenhuis Leuven (Belgium)) ;
Universitat Autònoma de Barcelona
Colorectal cancer (CRC) is a frequently lethal disease with heterogeneous outcomes and drug responses. To resolve inconsistencies among the reported gene expression-based CRC classifications and facilitate clinical translation, we formed an international consortium dedicated to large-scale data sharing and analytics across expert groups. [...]
2015 - 10.1038/nm.3967
Nature Medicine, Vol. 21, Num. 11 (November 2015) , p. 1350-1356
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